DHEA-S
Dehydroepiandrosterone sulfate (DHEA-S) is an androgen, a male sex
hormone that is present in the blood of both men and women. It has a
role to play in developing male secondary sexual characteristics at
puberty, and it can be metabolized by the body into more potent
androgens, such as testosterone and androstenedione, or can be changed
into the female hormone estrogen.
DHEAS is produced by the adrenal
cortex, the outer layer of the adrenal glands, with smaller amounts
being produced by the woman's ovaries and man's testes.
DHEAS secretion
is controlled by the pituitary hormone adrenocorticotropic hormone
(ACTH) and by other pituitary factors.
Since
DHEAS is primarily
produced by the adrenal glands, it is useful as a marker for adrenal
function. Adrenal tumors, cancers, and hyperplasia can lead to the
overproduction of
DHEAS. While elevated levels may not be noticed in
adult men, they can lead to amenorrhea and visible symptoms of
virilization. These changes vary in severity and may include: a deeper
voice, hirsutism, male pattern baldness, muscularity, acne, enlargement
of the Adam’s apple. Women with polycystic ovary syndrome tend to have
elevated levels of
DHEAS.
Product Specifications:
- Product code: GDB715125
- Calibrators: 0 , 0.2, 1, 2, 4 & 8 µg/ml
- Sample: 10 µl
- Sensitivity: 0.025 µg/ml
- Total Time: 45 Minutes
- Shelf Life: 18 Months