17-OHP
17-Hydroxyprogesterone is a C-21 steroid hormone produced during the
synthesis of glucocorticoids and sex steroids. As a hormone,
17-OHP also
interacts with the progesterone receptor.
Measurements of
17-OHP levels are useful in the evaluation of patients with suspected
congenital adrenal hyperplasia (CAH) as the typical enzymes that are
defective, namely 21-hydroxylase and 11β-hydroxylase, lead to a build-up
of
17-OHP.
In contrast, the rare patient with 17α-hydroxylase
deficiency will have very low or undetectable levels of
17-OHP.
17-OHP
levels can also be used to measure contribution of progestational
activity of the corpus luteum during pregnancy as progesterone but not
17-OHP is also contributed by the placenta.
The application of
17-OHP has been shown to be useful to delay premature labor in pregnancy.
Product Specifications:
- Product code: GDB715225
- Calibrators: 0 , 0.1, 0.5, 1.0, 5, 10 ng/ml
- Sample: 25 µl
- Sensitivity: 0.077 ng/ml
- Total Time: 80 Minutes
- Shelf Life: 18 Months